Table 1. APN‐KO mice exhibit attenuated myocardial immune cell infiltration in CVB3 myocarditis
MethodMeasureWTAPN‐KOWT CVB3APN‐KO CVB3
qRT‐PCRNkp46/HPRT10.0011 ± 0.00010.0013 ± 0.00010.0481 ± 0.0088a0.0224 ± 0.0033b
qRT‐PCRF4‐80/HPRT10.1984 ± 0.01330.2096 ± 0.00881.3049 ± 0.1679a0.7939 ± 0.0520
qRT‐PCRCD3Z/HPRT10.0031 ± 0.00020.0038 ± 0.00020.0630 ± 0.01350.0300 ± 0.0038b
qRT‐PCRCD4/HPRT10.0040 ± 0.00020.0034 ± 0.00040.0451 ± 0.0102a0.0206 ± 0.0027b
qRT‐PCRCD8a/HPRT10.0015 ± 0.00030.0019 ± 0.00020.0460 ± 0.00820.0223 ± 0.0034b
IHCCD11b+cells/mm211.82 ± 2.108.82 ± 2.26813.73 ± 124.04a297.65 ± 66.93
  • Mean ± SEM

  • a WT CVB3 versus WT

  • b APN‐KO CVB3 versus WT CVB3