Table 2. Histology after intravesical administration in WT and MIF KO mice
WTMIF KO
InflammationEdemaInflammationEdema
(A)
PAR4 scramble0.0 ± 0.00.0 ± 0.0 (n = 6)0.7 ± 0.30.3 ± 0.3 (n = 3)
PAR40.0 ± 0.00.0 ± 0.0 (n = 5)0.8 ± 0.50.8 ± 0.5 (n = 4)
(B)
PBS1.0 ± 0.61.0 ± 0.6 (n = 5)0.8 ± 0.21.2 ± 0.4 (n = 5)
dsHMGB10.5 ± 0.51.0 ± 0.5 (n = 6)0.7 ± 0.31.3 ± 0.4 (n = 6)
  • value: mean ± SE.