Table 1. Micturition after intravesical administration in WT and MIF KO mice
WTMIF KO
Volume (μL)FrequencyVolume (μL)Frequency
(A)
PAR4 scramble257 ± 11.43.3 ± 0.3 (n = 6) 632 ± 101 ** 1.0 ± 0.0** (n = 3)
PAR4235 ± 24.34.6 ± 0.9 (n = 5)417 ± 84.91.8 ± 0.5 (n = 4)
(B)
PBS301 ± 35.23.0 ± 0.3 (n = 5) 675 ± 66.9 ** 1.2 ± 0.2** (n = 5)
dsHMGB1265 ± 25.54.0 ± 1.0 (n = 6)485 ± 97.31.8 ± 0.4 (n = 6)
  • (A) **< 0.01 compared to WT PAR4 scramble (B) **< 0.01 compared to WT PBS; value: mean ± SE. Bold indicates significance value.