Table 2. Regulation of mRNA expression of MKPs in human skeletal muscle at baseline after acute exercise
MKPs0 h versus pre‐exercise2 h versus pre‐exercise
AllControlDysglycemicAllControlDysglycemic
DUSP5 10.85 ± 1.28 11.18 ± 1.72 10.45 ± 2.00 1.25 ± 0.141.34 ± 0.251.16 ± 0.13
DUSP2 6.77 ± 1.48 7.45 ± 2.29 5.96 ± 1.87 8.31 ± 0.94 9.36 ± 1.58 7.16 ± 0.90
DUSP1 4.00 ± 0.55 4.45 ± 0.79 3.47 ± 0.76 0.41 ± 0.07 0.39 ± 0.07 0.44 ± 0.09
DUSP8 2.19 ± 0.19 2.42 ± 0.31 1.91 ± 0.15 1.23 ± 0.111.26 ± 0.191.19 ± 0.11
DUSP4 1.97 ± 0.30 2.16 ± 0.42 1.74 ± 0.45 2.36 ± 0.34 2.73 ± 0.55 1.96 ± 0.38
DUSP16 1.51 ± 0.05 1.52 ± 0.07 1.50 ± 0.08 1.15 ± 0.04 1.22 ± 0.05 1.09 ± 0.07
DUSP10 1.23 ± 0.07 1.20 ± 0.07 1.26 ± 0.13 0.56 ± 0.05 0.59 ± 0.09 0.51 ± 0.05
DUSP70.99 ± 0.041.00 ± 0.060.97 ± 0.04 0.72 ± 0.04 0.74 ± 0.07 0.71 ± 0.05
DUSP6 0.62 ± 0.06 0.61 ± 0.07 0.63 ± 0.09 0.72 ± 0.06 0.72 ± 0.09 0.73 ± 0.07
  • Data represent mean fold changes ± SEM for all participants together (n = 24) or for separate groups (n = 11, controls; n = 13, dysglycemics); P‐values were calculated by paired Student's t‐test, P < 0.05 versus pre‐exercise (bold). Baseline pre‐exercise values are presented in Table 1. MKPs, MAPK phosphatases; DUSP, dual specificity phosphatase.