Table 1. Hemodynamic variables at baseline, 30 min, and 60 min after drinking decaffeinated (Placebo) and caffeinated coffee (Coffee)
PlaceboCoffee
base30 min60 minbase30 min60 min
HR (bpm)68.1 ± 13.364.4 ± 13.466.3 ± 15.373.6 ± 10.168.7 ± 12.469.4 ± 14.4
SBP (mmHg)114.3 ± 5.2117.9 ± 7.3119.6 ± 7.5a117.2 ± 6.7130.6 ± 8.5a,b134.7 ± 8.9a,b
DBP (mmHg)69.1 ± 6.072.0 ± 7.076.7 ± 9.5a66.8 ± 4.978.3 ± 6.7a,b80.4 ± 6.1a
MAP (mmHg)84.2 ± 5.187.2 ± 6.191.0 ± 7.9a83.6 ± 4.896.7 ± 6.8a,b98.5 ± 5.8a,b
Pulse pressure (mmHg)45.2 ± 3.945.8 ± 6.142.9 ± 6.550.4 ± 4.852.3 ± 3.454.3 ± 7.9
Systolic MCAv (cm/s)88.8 ± 10.986.7 ± 14.483.6 ± 12.988.9 ± 13.278.6 ± 14.077.2 ± 11.7
Diastolic MCAv (cm/s)36.4 ± 5.236.8 ± 6.136.2 ± 6.137.0 ± 4.532.7 ± 5.2a32.1 ± 3.7a
Mean MCAv (cm/s)53.8 ± 6.253.5 ± 7.552.1 ± 7.454.3 ± 6.648.0 ± 7.6a47.1 ± 5.8a
Pulse MCAv (cm/s)52.4 ± 7.949.9 ± 11.747.3 ± 8.951.9 ± 10.345.9 ± 9.445.1 ± 8.7
MCA PI0.99 ± 0.100.95 ± 0.150.94 ± 0.110.96 ± 0.100.98 ± 0.070.99 ± 0.07
MCA CVCi (cm/s/mmHg)0.65 ± 0.070.61 ± 0.100.57 ± 0.10a0.66 ± 0.090.50 ± 0.06a,b0.48 ± 0.06a,b
baPWV (cm/s)1056 ± 871067 ± 1211064 ± 1341030 ± 821117 ± 143a1131 ± 126a,b
petCoz (mmHg)38.6 ± 2.238.7 ± 1.838.3 ± 1.638.3 ± 2.337.0 ± 1.9a,b36.1 ± 2.7a,b
  • Values are mean ± SD (n = 10). HR, Heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; MCA, middle cerebral artery; MCAv, MCA blood velocity; MCA PI, pulsatility index of MCAv; MCA CVCi, MCA cerebral vascular conductance index; baPWV, brachial‐ankle pulse wave velocity; PETCO2, end‐tidal partial pressure of carbon dioxide.

  • a Different from baseline (P < 0.05).

  • b Different from Placebo (P < 0.05).