Table 1. Biometrics and blood chemistry parameters in C57Bl/6J and FVB/N mice that were fed the chow diet or HFD
C57BL6/J ChowC57BL6/J HFDFVB/N ChowFVB/N HFDC57BL6/JFVB/NC57BL6/J vs. FVB/N
MeanSEMnMeanSEMnMeanSEMnMeanSEMnChow vs. HFDChow vs. HFD
Body weight (g)27.00.691238.90.891232.41.351243.30.8612P < 0.0001P < 0.0001P < 0.01
Body length (cm)9.780.06129.980.09129.870.051110.230.0811n.s.P < 0.01n.s.
Weight gain (g)3.20.941215.30.72125.41.011216.30.6412P < 0.0001P < 0.0001n.s.
Food intake (g)2803.5121883.8123284.3122379.412P < 0.0001P < 0.0001P < 0.0001
Food intake (kcal)11321412105021121327171213215212P < 0.01n.s.P < 0.0001
Liver (g)1.20.1161.30.0461.40.04112.50.1511n.s.P < 0.0001n.s.
iBAT (g)0.120.01960.190.01960.240.036110.280.03511P < 0.05n.s.P < 0.05
subWAT (g)0.750.1062.20.2162.40.0243.50.094P < 0.0001P < 0.0001P < 0.0001
epiWAT (g)0.580.06121.970.12121.110.09110.920.0611P < 0.0001n.s.P < 0.001
epiWAT/B.W (100a)2.110.15124.990.26123.780.34112.260.1411P < 0.0001P < 0.001P < 0.001
epiWAT/length (10a)0.600.06121.980.13121.120.09110.890.0511P < 0.0001P < 0.05P < 0.001
Leptin (pg/mL)1575367115121813101521238631155528P < 0.01P < 0.05n.s.
Serum insulin (pmol/L)24547116821271135511311100313011P < 0.01P < 0.01n.s.
Blood glucose (mmol/L)a9.30.241211.50.251210.30.581214.40.7412P < 0.0001P < 0.001n.s.
HOMA‐IRa5.90.666193.06318.84161474P < 0.01P < 0.05P < 0.01
QUICKIa0.300.00460.260.00560.250.00740.210.0054P < 0.001P < 0.01P < 0.001
Serum triglycerides (mg/dL)271.76357.959710.57554.38n.s.P < 0.01P < 0.0001
Serum cholesterol (mg/dL)1294.261637.251667.271856.58P < 0.01n.s.P < 0.01
  • Basal glycemia, determined by GTT.

  • a Basal insulin and glycemia levels (determined by the GTT at time 0) were used to calculate HOMA‐IR and QUICKI.