Sample times | Iohexol one‐compartment | Iohexol trapezoidal | Iohexol two‐compartment | ||||||
---|---|---|---|---|---|---|---|---|---|

R^{2} | Bias/Precisiona | 10% Acb | R^{2} | Bias/Precisiona | 10% Acb | R^{2} | Bias/Precisiona | 10% Acb | |

30, 60 | 0.87 | 0.02 ± 0.27 | 72.7 | 0.86 | 0.00 ± 0.32 | 50.0 | 0.84 | 0.04 ± 2.79 | 69.0 |

60, 90 | 0.90 | 0.18 ± 0.95 | 76.7 | 0.92 | 0.16 ± 0.94 | 47.7 | 0.91 | 0.19 ± 0.95 | 72.5 |

90, 120 | 0.43 | 0.15 ± 0.37 | 73.3 | 0.73 | 0.13 ± 0.43 | 51.1 | 0.66 | 0.12 ± 0.42 | 66.7 |

30, 90 | 0.97 | −0.02 ± 0.12 | 91.1 | 0.96 | −0.04 ± 0.15 | 66.7 | 0.94 | 0.01 ± 0.18 | 83.3 |

60, 120 | 0.82 | −0.04 ± 0.23 | 53.3 | 0.91 | −0.06 ± 0.19 | 66.7 | 0.95 | −0.01 ± 0.32 | 54.8 |

Each animal (

*N*= 8) at each evaluation (*N*= 6) is an individual data point (*N*= 44–48). Linear regression coefficients (*R*^{2}) weighted 1/*C*^{2}.↵a Bias or absolute bias is calculated as reference method – two‐sample clearance. Precision is the standard deviation of bias.

↵b 10% Ac or 10% Accuracy is the percentage of sample values with a % bias of <10. % Bias is calculated by dividing the absolute bias by the mean of the two measures.