Table 2. Allele and genotype frequencies of the polymorphisms presenting significant results between international athletes and controls
Gene symbolPolymorphism rs numberAllele frequencyGenotype frequency, n (%)International Athletes versus controls P value (OR [95% CI]) Genetic modela
AlleleControlRegional athleteNational athleteInternational athleteGenotypeControlRegional athleteNational athleteInternational athlete
ACTN3 C/T
rs1815739
C0.470.430.480.56CC132 (20.3)3 (13.4)20 (21.3)16 (26.7) 0.042 (2.03 [0.98–4.21])
C‐dominant
T0.530.570.520.44CT346 (53.3)12 (57.1)50 (53.2)35 (58.3)
TT171 (26.4)6 (28.6)24 (25.5)9 (15.0)
GNB3 C>T
rs5443
C0.510.380.560.59CC166 (25.6)5 (23.8)31 (33.3)17 (28.3) 0.0072 (0.35 [0.15–0.83])
T‐recessive
T0.490.620.440.41CT327 (50.4)6 (28.6)42 (45.2)37 (61.7)
TT156 (24.0)10 (47.6)20 (21.5)6 (10.0)
  • a A most fitted genetic model based on Akaike information criterion is shown.